Hearing loss in congenital Zika virus.
نویسنده
چکیده
The recent article on ‘‘Hearing loss in congenital Zika virus’’ is very interesting.1 Leal et al. reported an interesting case of sensorineural hearing loss in a case of congenital Zika virus.1 In fact, it is no doubt that Zika virus can induce teratogenic effect and the main pathology is on the fetal neurological system. However, the myth is the exact mechanism underlying the hearing loss in the present case. In fact, the direct viral invasion is believe to be the main pathogenesis of neurological defect in congenital Zika virus infection.2 In the present report, the interesting concern is the nonfatal brain involvement but neuro-auditory system defect. Generally, the brain pathology in congenital Zika virus infection is at cortex3 and not common at brain stem, hence, it should rarely involve the neuro-auditory system. Indeed, there are many viral infections that can result in congenital neurosensory hearing loss such as Cytomegalovirus (CMV) infection.3 There are many possible explanation for the present interesting case. In the present case, since there is no clear evidence when the mother got infection, the Zika virus intra-utero infection might occur after the brain development. There might also be prior silent
منابع مشابه
Hearing Loss in Infants with Microcephaly and Evidence of Congenital Zika Virus Infection - Brazil, November 2015-May 2016.
Congenital infection with Zika virus causes microcephaly and other brain abnormalities (1). Hearing loss associated with other congenital viral infections is well described; however, little is known about hearing loss in infants with congenital Zika virus infection. A retrospective assessment of a series of 70 infants aged 0-10 months with microcephaly and laboratory evidence of Zika virus infe...
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Dear Editors, The paper by van der Linden et al., “Discordant clinical outcomes of congenital Zika virus infection in twin pregnancies”1 provides additional information in a story that has placed Zika firmly in the company of other infections such as cytomegalovirus and toxoplasmosis that can cause birth defects in the central nervous system. Unlike these other congenital infections, however, Z...
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In 2015, during the outbreak of Zika virus (ZIKV) in Brazil, we identified 3 cases of acute hearing loss after exanthematous illness. Serology yielded finding compatible with ZIKV as the cause of a confirmed (n = 1) and a probable (n = 2) flavivirus infection, indicating an association between ZIKV infection and transient hearing loss.
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ورودعنوان ژورنال:
- Brazilian journal of otorhinolaryngology
دوره 83 2 شماره
صفحات -
تاریخ انتشار 2017